EE Chapter 38 Drug Delivery Systems Q&A (1 OF 36) Sample Questions
1. We can increase the bioavailability of an ophthalmic preparation by:
I. Increasing viscosity of preparation
II. Addition of a sticking agent
III. Increasing volume of the inserted dose
- A. I only
- B. III only
- C. I and II only
- D. II and III only
- E. All are correct
Tips: Hydroxypropyl methyl cellulose (HPMC) and CMC increase viscosity in ophthalmic preparations.
1. Read the question. This is a K-type of question that asks you the right combination choices.
2. Look for the cues and keywords. Your cues here are increased bioavailability. Keyword opthalmic. So, you are asked about means to maximize absorption of the preparation. Look for choices that suggest a longer contact time between the cornea and the opthalmics. Choice III is incorrect because volume does not secure tenacity of the preparation unto the eyes. So, remove all options with III.
3. Therefore, the correct answer is C.