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Chapter 89 Drugs in Elderly Populations Sample Questions

1. A doctor wants to recommend treatment and prevention of allergic rhinitis in a 70-year-old Parkinson's disease patient. What is the best choice?

A. DiMENhydrinate
B. DiPHENhydramine
C. Cetirizine
D. Desloratadine

Answer

Ans: D

Tips: Use of cetirizine in standard doses is associated with more sedation compared with placebo, but less than first-generation antihistamines. Administration of standard doses of loratadine and desloratadine results in an incidence of sedation equivalent to placebo; however, drowsiness has been reported at higher than recommended doses, or rarely in susceptible individuals at recommended doses. Fexofenadine appears to be nonsedating, even at increased doses.

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