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Chapter 81 Tuberculosis Q&A (1 of 6) Sample Questions

1. A 30-year-old pregnant woman in her first trimester has a latent tuberculosis (TB) infection (LTBI). She is living in an INH-resistant area. The best choice her doctor can give her is:

A. Wait until the second trimester to initiate treatment
B. Start immediate INH + Rifadin
C. Rifadin for 4 months
D. INH+RIF+PZA+EM for 6 months

Answer

Ans: C

Tips: This is not an active therapy, therefore no aggressive therapy required; the need for combinations is not needed. Patient is in INH-resistant area thus better option is Rifadin for 4 months. However, in patients without high risk of disease, withhold latent therapy until 3 months postpartum to reduce the risk of hepatotoxicity.

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