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Chapter 67 Acne Q&A (1 of 25) Sample Questions

1. DJ is a 17-year-old female who complains of worsening acne over the past four and half months with severe inflammation, papules and pustules and possibly few nodules. Which of the following is the most appropriate combination to provide a comedolytic and anti-inflammatory effect?

A. Benzoyl peroxide and Tetracycline
B. Benzoyl peroxide and Tretinoin
C. Benzoyl peroxide and Isotretinoin
D. Benzoyl peroxide and combined oral contraceptive

Answer

Ans: B

Tips: RxTx/CTC. Acne. For moderate acne characterized by papules and pustules and possibly a few nodules, the following Topical combination therapy should consist of:
Benzoyl peroxide and topical retinoid OR
Benzoyl peroxide and topical antibiotic OR
Benzoyl peroxide and topical retinoid and topical antibiotic
Topical retinoids are the most powerful comedolytic agents, yet still take months to be effective. They are also effective for inflammatory lesions. Tretinoin is the most cost effective but also the most photosensitizing. Adapalene is the least irritating and tazarotene is the most potent.

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