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Chapter 45 – Autoimmune Disorders (QE) Sample Questions

1. A 32-year-old woman presents to your pharmacy with a prescription for glatiramer acetate injection. She explains that she was recently diagnosed with a neurological condition after experiencing episodes of visual disturbances, numbness in her limbs, and muscle weakness. Her neurologist mentioned that this medication is part of her long-term disease-modifying therapy to reduce relapses and slow progression. What is glatiramer acetate primarily used for?

A. Multiple Sclerosis
B. Age-related Macular Degeneration (AMD)
C. Systemic Lupus Erythematosus
D. Neuropathic Pain

Answer

Ans: A

Tips: Glatiramer acetate is an immunomodulator used in the treatment of relapsing-remitting multiple sclerosis (RRMS).
• It works by mimicking myelin basic protein, shifting the immune response from pro-inflammatory (Th1) to anti-inflammatory (Th2), thereby reducing demyelination.
• It is not used for AMD, lupus, neuropathic pain, or giant cell arteritis.
• Other disease-modifying therapies for MS include interferon-β, natalizumab, fingolimod, ocrelizumab, etc.

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