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Chapter 4 – Psychosis (QE) Sample Questions

1. A 38-year-old male with schizophrenia has been stable on aripiprazole long-acting injection (Abilify Maintena®) 400 mg IM monthly for 12 months. His last injection was administered 7 weeks ago. He presents today after missing his scheduled appointment. He is currently asymptomatic. What is the MOST appropriate management?

A. Administer one 400 mg injection immediately and resume monthly schedule
B. Administer 400 mg IM today plus oral aripiprazole 10–20 mg daily for 14 days
C. Restart full initiation protocol with two 400 mg injections 2 weeks apart
D. Delay injection until psychiatric reassessment

Answer

Ans: B

Explanation: Administer 400 mg IM today plus oral aripiprazole 10–20 mg daily for 14 days
If the 4th or subsequent dose is missed and >6 weeks have elapsed since the last injection, the patient requires re-establishment of therapeutic levels. Management includes one 400 mg injection plus 14 days of oral aripiprazole supplementation.

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