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Chapter 37 Inflammatory Bowel Disease (IBD) Sample Questions

1. A 28 year old pregnant woman in her first trimester is diagnosed with mild ulcerative colitis. Complete blood test was done with an elevated levels of WBC, platelet, ESR and CRP. T: 38°C. Which of the following is the appropriate initial treatment?

A. Prednisone
B. 5-ASA
C. Sulfasalazine
D. 5-ASA suppositories

Answer

Ans: B

Tips: CTC/RxTx. Inflammatory Bowel Disease. Aminosalicylates are considered low risk in pregnancy and patients can be safely switched from sulfasalazine to 5-ASA when initially on sulfasalazine as this medication has risk of anti-folate effects. Corticosteroids are avoided especially during the first trimester due to reports of oral clefts in newborn.

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