Chapter 37 – Nausea & Vomiting (QE) Sample Questions
1. KT, a 29-year-old woman who is 9 weeks pregnant, presents to your pharmacy with complaints of moderate nausea and vomiting. She has already attempted her on dietary and lifestyle modifications and used pyridoxine 250 mg Q8h without significant improvement. She now seeks an over-the-counter (OTC) medication that is safe for her baby. She has no known drug allergies. Considering KT's pregnancy and desire for safety, which of the following OTC medications is most appropriate for her to use for nausea and vomiting?
- A. Dimenhydrinate (Dramamine) and refer patient to see the doctor if no improvement 2 days
- B. Ondansetron and refer patient to see the doctor if no improvement 2 days
- C. Pyridoxine plus doxylamine (Diclectin) and refer patient to see the doctor if no improvement 2 days
- D. Ginger tablets and refer patient to see the doctor if no improvement 2 days
Ans:
A
Tips: Expert opinion suggests that first-line options for moderate to severe NVP include dimenhydrinate, diphenhydramine and promethazine; second-line agents include chlorpromazine, methylprednisolone, metoclopramide and prochlorperazine
Based upon Health Canada released safety labelling updates in 2020 recommending against use of ondansetron in pregnancy
Save My Preference